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HLA-B ANTIGENS
Descriptors Found:
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DeCS
Descriptor
English
:
HLA-B Antigens
Descriptor
Spanish
:
Antígenos HLA-B
Descriptor
Portuguese
:
Antígenos HLA-B
Synonyms
English
:
Antigens, HLA B
Antigens, HLA-B
HLA B Antigens
HLA-B
Tree Number:
D12.776.395.550.489.500
D12.776.543.550.439.500
D23.050.301.500.100.500
D23.050.301.500.450.380
D23.050.705.552.100.500
D23.050.705.552.450.380
Definition
English
:
Class I human
histocompatibility
(HLA) surface
antigens
encoded by more than 30 detectable
alleles
on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these
antigens
(e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T
lymphocytes.
Indexing Annotation
English
:
general; prefer specifics
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23670
Unique Identifier:
D015235
Occurrence in VHL
:
Similar:
DeCS